MANE, one of the world’s leading flavour and fragrance manufacturers, and Arzeda, a pioneer in AI-driven protein design, today announced the next phase of their strategic partnership. Under the new agreement, MANE has acquired an exclusive global license to produce and commercialise Arzeda’s groundbreaking ViaLeaf™ Reb M, a revolutionary process that uses Nobel Prize-winning technology.
The license enables MANE to manage the entire Reb M value chain, from production through commercialisation. This strategic milestone builds on the successful collaboration between MANE and Arzeda announced in March 2026 and significantly advances the companies’ shared goal of making high-quality, natural sugar-reduction solutions more accessible to the global food and beverage industry.
“This new step in our partnership with Arzeda reflects our commitment to delivering innovative, high-performance solutions to our customers,” said Samantha Mane, CEO of the MANE Group. “By combining Arzeda’s breakthrough technology with MANE’s production, flavour creation, application and commercial expertise, we can now offer the market a fully integrated Reb M solution that delivers outstanding taste performance and competitive economics.”
Innovative Protein Design Technology
Through Arzeda’s innovative protein design technology and MANE’s global manufacturing, formulation and commercial capabilities, customers will benefit from a scalable Reb M solution that delivers superior taste performance, reliable supply and an exceptional quality-to-cost ratio.
Reb M is widely recognised as the most desirable steviol glycoside for its clean, sugar-like sweetness and neutral flavor profile. Arzeda’s proprietary technology has transformed the economics of Reb M production and MANE’s industrial expertise will enable large-scale deployment to meet growing market demand for natural sugar-reduction solutions.
“MANE is uniquely positioned to unlock the full potential of ViaLeaf Reb M, the first-ever product enabled by AI-driven protein design to reach the market,” said Alexandre Zanghellini, PhD, CEO of Arzeda. “By entrusting MANE with production and commercialisation, we are combining Arzeda’s innovation capabilities with MANE’s global scale and industry leadership to accelerate the adoption of next-generation sweetening solutions worldwide.”
The expanded partnership will help food and beverage manufacturers meet growing consumer demand for lower-sugar products while maintaining taste and supporting clean-label development. By integrating technological innovation with industrial-scale production, MANE and Arzeda are setting a new benchmark for natural sweetening solutions.
